Improved Arterial Compliance by a Novel Advanced Glycation End-Product Crosslink Breaker
نویسندگان
چکیده
منابع مشابه
Improved arterial compliance by a novel advanced glycation end-product crosslink breaker.
BACKGROUND Arterial stiffening with increased pulse pressure is a leading risk factor for cardiovascular disease in the elderly. We tested whether ALT-711, a novel nonenzymatic breaker of advanced glycation end-product crosslinks, selectively improves arterial compliance and lowers pulse pressure in older individuals with vascular stiffening. METHODS AND RESULTS Nine US centers recruited and ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2001
ISSN: 0009-7322,1524-4539
DOI: 10.1161/hc3801.097806